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While conventional magnetic resonance imaging (MRI) in multiple sclerosis (MS) primarily evaluates focal lesions, the normal-appearing white matter (NAWM) encompasses brain tissue that appears radiologically normal but harbors subtle pathological changes that contribute to the overall disease burden. The aim of this study was to investigate the role of T1rho MRI in characterising distance-dependent microstructural changes in the perilesional NAWM in patients with relapsing-remitting multiple sclerosis (RRMS).
Pubmed ID: 41081152
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Software library of image analysis and statistical tools for fMRI, MRI and DTI brain imaging data. Include registration, atlases, diffusion MRI tools for parameter reconstruction and probabilistic taractography, and viewer. Several brain atlases, integrated into FSLView and Featquery, allow viewing of structural and cytoarchitectonic standard space labels and probability maps for cortical and subcortical structures and white matter tracts. Includes Harvard-Oxford cortical and subcortical structural atlases, Julich histological atlas, JHU DTI-based white-matter atlases, Oxford thalamic connectivity atlas, Talairach atlas, MNI structural atlas, and Cerebellum atlas.
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