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Study of linear energy transfer effect on rib fracture in breast cancer patients receiving pencil-beam-scanning proton therapy.

Yunze Yang | Kimberly R Gergelis | Jiajian Shen | Arslan Afzal | Trey C Mullikin | Robert W Gao | Khaled Aziz | Dean A Shumway | Kimberly S Corbin | Wei Liu | Robert W Mutter
Medical physics | 2025

In breast cancer patients treated with pencil-beam scanning proton therapy (PBS), the increased linear energy transfer (LET) near the end of the proton range can affect nearby ribs. This may associate with a higher risk of rib fractures.

Pubmed ID: 40102627

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Associated grants

  • Agency: NCI NIH HHS, United States
    Id: P30 CA015083
  • Agency: NCI NIH HHS, United States
    Id: R01 CA261932
  • Agency: NCI NIH HHS, United States
    Id: R01 CA272602
  • Agency: NCI NIH HHS, United States
    Id: R01 CA280134

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MATLAB (tool)

RRID:SCR_001622

Multi paradigm numerical computing environment and fourth generation programming language developed by MathWorks. Allows matrix manipulations, plotting of functions and data, implementation of algorithms, creation of user interfaces, and interfacing with programs written in other languages, including C, C++, Java, Fortran and Python. Used to explore and visualize ideas and collaborate across disciplines including signal and image processing, communications, control systems, and computational finance.

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