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MRI quantified enlarged perivascular space volumes as imaging biomarkers correlating with severity of anxiety depression in young adults with long-time mobile phone use.

Li Li | Yalan Wu | Jiaojiao Wu | Bin Li | Rui Hua | Feng Shi | Lizhou Chen | Yeke Wu
Frontiers in psychiatry | 2025

Long-time mobile phone use (LTMPU) has been linked to emotional issues such as anxiety and depression while the enlarged perivascular spaces (EPVS), as marker of neuroinflammation, is closely related with mental disorders. In the current study, we aim to develop a predictive model utilizing MRI-quantified EPVS metrics and machine learning algorithms to assess the severity of anxiety and depression symptoms in patients with LTMPU.

Pubmed ID: 40051766

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R Project for Statistical Computing (tool)

RRID:SCR_001905

Software environment and programming language for statistical computing and graphics. R is integrated suite of software facilities for data manipulation, calculation and graphical display. Can be extended via packages. Some packages are supplied with the R distribution and more are available through CRAN family.It compiles and runs on wide variety of UNIX platforms, Windows and MacOS.

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RRID:SCR_002798

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SPSS (tool)

RRID:SCR_002865

Software package used for interactive, or batched, statistical analysis in social science, health sciences and marketing. Software platform offers advanced statistical analysis, a library of machine-learning algorithms, text analysis, open-source extensibility, integration with big data and deployment into applications.Versions that were produced by SPSS Inc. before the IBM acquisition (Versions 18 and earlier) would be given origin or publisher of SPSS Inc. in Chicago.

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Adobe Illustrator (tool)

RRID:SCR_010279

Vector graphics software to create digital graphics, illustrations, and typography for several types of media: print, web, interactive, video, and mobile.

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RRID:SCR_013726

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GE HealthCare (tool)

RRID:SCR_025461

Provides digital infrastructure, data analytics and decision support tools to help in diagnosis, treatment and monitoring of patients.

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