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Catalpalactone protects rats nerve function from hypoxic lesion by polarizing microglial cells toward M2 phenotype.

Yu Wang | Qi Wang | Xin Sui | Mingxing Guo | Li Li | Weiwei Jia | Yinan Tian | Qi Lu | Bo Wang
European journal of medical research | 2025

Ischemic brain injury results in high disability due to neuroinflammation and oxidative stress, and M1/M2 polarization of glial cells plays a key role in neuroinflammation. This research explored the protective effect of Catalpalactone on middle cerebral artery occlusion (MCAO)-induced brain injury and its underlying regulation mechanism in rats.

Pubmed ID: 39940010

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Associated grants

  • Agency: the study of Basic research funding for higher education institutions in Heilongjiang Province,
    Id: 2022-KYYWF-0802

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FlowJo (tool)

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