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Comprehensive analysis of KLF family reveals KLF6 as a promising prognostic and immune biomarker in pancreatic ductal adenocarcinoma.

Jiayu Lin | Pengyi Liu | Keyan Sun | Lingxi Jiang | Yang Liu | Yishu Huang | Jia Liu | Minmin Shi | Jun Zhang | Ting Wang | Baiyong Shen
Cancer cell international | 2024

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest tumors worldwide, with extremely aggressive and complicated biology. Krüppel-like factors (KLFs) encode a series of transcriptional regulatory proteins and play crucial roles in a variety of processes, including tumor cell differentiation and proliferation. However, the potential biological functions and possible pathways of KLFs in the progression of PDAC remain elusive.

Pubmed ID: 38773440

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Associated grants

  • Agency: the National Nature Science Foundation of China,
    Id: 82273356

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RRID:SCR_014555

A portal that provides visualization, analysis and download of large-scale cancer genomics data sets.

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