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Lifestyle intervention in children with obesity and nonalcoholic fatty liver disease (NAFLD): study protocol for a randomized controlled trial in Ningbo city (the SCIENT study).

Ping-Ping Zhang | You-Xin Wang | Fang-Jing Shen | Yun-Fei Xing | Jia-Ying Gu | Xue-Ying Li | Han Jin | Shi-Feng Jin | Miao Xu | Hai-Jun Wang | Hui Wang | Li Li
Trials | 2024

The increasing prevalence of childhood obesity has become an urgent public health problem, evidence showed that intervention for childhood obesity bring enormous health benefits. However, an effective individualized intervention strategy remains to be developed, and the accompanying remission of related complications, such as nonalcoholic fatty liver disease (NAFLD), needs to be assessed. This study aimed to develop an m-Health-assisted lifestyle intervention program targeting overweight/obese children and assess its effectiveness on indicators of adiposity and NAFLD.

Pubmed ID: 38504343

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Associated grants

  • Agency: The Major Science and Technology Projects for Health of Zhejiang Province,
    Id: WKJ-ZJ-2216
  • Agency: The Cyrus Tang Foundation for Young Scholar 2022,
    Id: 2022-B126

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Sample size software for clinical trial, pharmaceutical, and other medical research where sample size calculation or evaluation is needed. Provides sample size tools for statistical test and confidence interval scenarios. Each tool has been validated with published articles and texts.

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