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Sustained morphine exposure alters spinal NMDA receptor and astrocyte expression and exacerbates chronic pain behavior in female rats.

Sara V Gonçalves | Stephen G Woodhams | Li Li | Gareth J Hathway | Victoria Chapman
Pain reports | 2024

Sustained opioid use has long-term negative impacts on future pain experience, particularly in women. This study aimed to investigate the underlying spinal neurobiology of this clinical observation in an experimental model of joint pain.

Pubmed ID: 38482044

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SD (tool)

RRID:RGD_70508

Rattus norvegicus with name SD from RGD.

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