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The mystery of transient pregnancy-induced cushing's syndrome: a case report and literature review highlighting GNAS somatic mutations and LHCGR overexpression.

Yufei Li | Jianfan Lin | Shien Fu | Li Li | Zhenxing Huang | Haiyan Yang | Xinghuan Liang | Yingfen Qin | Jia Zhou | Deyun Liu | Zuojie Luo
Endocrine | 2023

Transient pregnancy-induced Cushing's syndrome is a rare condition characterized by the manifestation of symptoms solely during pregnancy, which typically resolve spontaneously following delivery or miscarriage. While it has been established that GNAS is associated with adrenal tumors, its specific role in the pathogenesis of pregnancy-induced Cushing's syndrome remains uncertain.This work aims to examine the association between GNAS mutation and pregnancy-induced Cushing's syndrome.

Pubmed ID: 37828397

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