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Impact factors of Blastocystis hominis infection in persons living with human immunodeficiency virus: a large-scale, multi-center observational study from China.

Shun-Xian Zhang | Ji-Chun Wang | Zhong-Wei Li | Jin-Xin Zheng | Wen-Ting Zhou | Guo-Bing Yang | Ying-Fang Yu | Xiu-Ping Wu | Shan Lv | Qin Liu | Mu-Xin Chen | Yan Lu | Zhi-Hui Dou | Da-Wei Zhang | Wen-Wen Lv | Lei Wang | Zhen-Hui Lu | Ming Yang | Pei-Yong Zheng | Yue-Lai Chen | Li-Guang Tian | Xiao-Nong Zhou
Infectious diseases of poverty | 2023

Blastocystis hominis (Bh) is zoonotic parasitic pathogen with a high prevalent globally, causing opportunistic infections and diarrhea disease. Human immunodeficiency virus (HIV) infection disrupts the immune system by depleting CD4+ T lymphocyte (CD4+ T) cell counts, thereby increasing Bh infection risk among persons living with HIV (PLWH). However, the precise association between Bh infection risk and HIV-related biological markers and treatment processes remains poorly understood. Hence, the purpose of the study was to explore the association between Bh infection risk and CD4+ T cell counts, HIV viral load (VL), and duration of interruption in antiviral therapy among PLWH.

Pubmed ID: 37697423

Research resources used in this publication

None found

Antibodies used in this publication

None found

Associated grants

  • Agency: Three-year Action Plan for Promoting Clinical Skills and Innovation Ability of Municipal Hospitals.,
    Id: No.SHDC2022CRS039
  • Agency: National Natural Science Foundation of China,
    Id: No.81473022
  • Agency: Natural Science Foundation of Shanghai,
    Id: No.23ZR1464000
  • Agency: Natural Science Foundation of Shanghai,
    Id: No.23ZR1463900
  • Agency: The talent fund Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine,
    Id: LH001.007
  • Agency: Natural Science Foundation of Gansun Province,
    Id: 21JR7RA631
  • Agency: Natural Science Foundation of Gansu Province,
    Id: 21JR11RA182
  • Agency: Medical Innovation Research Special Project of the Shanghai 2021,
    Id: 21Y11922500
  • Agency: Medical Innovation Research Special Project of the Shanghai 2021,
    Id: 21Y11922400
  • Agency: Shanghai Natural Science Foundation,
    Id: 22ZR1462100
  • Agency: Research Ward Construction Project of Shanghai Hospital Development Center,
    Id: SHDC2022CRW006
  • Agency: Shanghai Municipal Education Commission Collaborative Innovation Cente,
    Id: A1-U21-205-902

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