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Denosumab biosimilar (LY06006) in Chinese postmenopausal osteoporotic women: A randomized, double-blind, placebo-controlled, multicenter phase III study.

Jiemei Gu | Hao Zhang | Qingyun Xue | Li Wang | Zhifeng Cheng | Yawei Zhang | Qifu Li | Lingqing Yuan | Yukun Li | Jin Dong | Yanan Huo | Xin Tang | Ling Hu | Xinjia Wang | Fei Hua | Lin Shen | Jinluo Cheng | Huimin Zhou | Youjia Xu | Tao Yang | Chuansuo Wang | Jin Xu | Jie Shen | Ying Zhang | Xiaomei Zhang | Dun Hong | Xiaoling Guan | Xinhua Xiao | Guang Wang | Yonghua Liu | Liujun Fu | Jianting Chen | Xigao Cheng | Yue Ding | Lijun Liu | Qi Yao | Xinchao Zhang | Lixin Li | Panjun Zhang | Chunying Deng | Chengyan Jiang | Li You | Kai Wang | Shimin Zhang | Jianzhong Xiao | Wei Liu | Xiaohong Du | Xianwen Shang | Tianrong Pan | Chen Lei | Shuren Guo | Zhenlin Zhang
Journal of orthopaedic translation | 2023

This study assessed the efficacy, safety, pharmacokinetics (PK), and immunogenicity profiles of a denosumab biosimilar (LY06006) in Chinese postmenopausal osteoporotic women with a high risk of fracture.

Pubmed ID: 36381249

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ClinicalTrials.gov (tool)

RRID:SCR_002309

Registry and results database of federally and privately supported clinical trials conducted in United States and around world. Provides information about purpose of trial, who may participate, locations, and phone numbers for more details. This information should be used in conjunction with advice from health care professionals.Offers information for locating federally and privately supported clinical trials for wide range of diseases and conditions. Research study in human volunteers to answer specific health questions. Interventional trials determine whether experimental treatments or new ways of using known therapies are safe and effective under controlled environments. Observational trials address health issues in large groups of people or populations in natural settings. ClinicalTrials.gov contains trials sponsored by National Institutes of Health, other federal agencies, and private industry. Studies listed in database are conducted in all 50 States and in 178 countries.

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