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Knockdown circTRIM28 enhances tamoxifen sensitivity via the miR-409-3p/HMGA2 axis in breast cancer.

Shiyong Yang | Changwu Zou | Yuxin Li | Xianguo Yang | Wei Liu | Guannan Zhang | Nina Lu
Reproductive biology and endocrinology : RB&E | 2022

Tamoxifen (TAM) is a frequently-used treatment for breast cancer (BC). But the TAM resistance seriously affects the patient therapeutic effect. Previous research indicated that circular RNAs (circRNAs) might participate in the regulatory processes of BC. Here, we discovered the parts of circular RNA tripartite motif-containing 28 (circTRIM28) in BC.

Pubmed ID: 36180890

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MDA-MB-231 (tool)

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NU/J (tool)

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