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LAP3 contributes to IFN-γ-induced arginine depletion and malignant transformation of bovine mammary epithelial cells.

Li Li | Fengyang Li | Xiuhong Hu | Zengshuai Wu | Wenbo Ren | Tingting Wang | Zhengchao Ji | Na Li | Jingmin Gu | Changjiang Sun | Xin Feng | Wenyu Han | Jing Huang | Liancheng Lei
BMC cancer | 2022

IFN-γ has been traditionally recognized as an inflammatory cytokine that involves in inflammation and autoimmune diseases. Previously we have shown that sustained IFN-γ induced malignant transformation of bovine mammary epithelial cells (BMECs) via arginine depletion. However, the molecular mechanism underlying this is still unknown.

Pubmed ID: 35941558

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Rabbit Anti-Cyclin A1 antibody (antibody)

RRID:AB_2904213

This polyclonal targets Cyclin A1

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HRP Goat Anti-Mouse IgG (H+L) (antibody)

RRID:AB_2769851

This unknown targets IgG (H+L)

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p44/42 MAPK (Erk1/2) Mouse monoclonal Antibody (antibody)

RRID:AB_2846228

This monoclonal targets p44/42 MAPK (Erk1/2)

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HDAC2 (3F3) Mouse monoclonal Antibody (antibody)

RRID:AB_10624871

This monoclonal targets HDAC2 (3F3) Mouse mAb

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LAP3 Antibody (antibody)

RRID:AB_2845613

This unknown targets LAP3

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Cyclin D1 antibody (antibody)

RRID:AB_10793718

This monoclonal targets Cyclin D1

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Phospho-ERK1/2 (Thr202/Tyr204) Antibody (antibody)

RRID:AB_2834432

This unknown targets Phospho-ERK1/2 (Thr202/Tyr204)

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GAPDH Rabbit mAb (antibody)

RRID:AB_2862549

This monoclonal targets

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ASS1 Antibody (antibody)

RRID:AB_2833984

This monoclonal targets ASS1

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Phospho-p38 MAPK (Thr180/Tyr182) Antibody (antibody)

RRID:AB_2835330

This unknown targets Phospho-p38 MAPK (Thr180/Tyr182)

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P27; KIP1 antibody (antibody)

RRID:AB_2880161

This polyclonal targets P27; KIP1

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HRP Goat Anti-Rabbit IgG (H+L) (antibody)

RRID:AB_2769854

This unknown targets IgG (H+L)

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