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Suppression of NF-κB signaling by ECN in an arthritic model of inflammation.

Amna Khan | Li Zhang | Chang Hu Li | Ashraf Ullah Khan | Bushra Shal | Adnan Khan | Sajjad Ahmad | Fakhar Ud Din | Zia Ur Rehman | Feng Wang | Salman Khan
BMC complementary medicine and therapies | 2022

The 7β-(3-ethyl-cis-crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone (ECN), a sesquiterpenoid isolated from the Tussilago farfara Linneaus (Asteraceae), was evaluated against acute Carrageenan and chronic complete Freund's adjuvant (CFA)-induced arthritis in mice.

Pubmed ID: 35698107

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Thermo Fisher Scientific (tool)

RRID:SCR_008452

Commercial vendor and service provider of laboratory reagents and antibodies. Supplier of scientific instrumentation, reagents and consumables, and software services.

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AutoDock (tool)

RRID:SCR_012746

Software suite of automated docking tools. Designed to predict how small molecules, such as substrates or drug candidates, bind to receptor of known 3D structure. AutoDock consist of AutoDock 4 and AutoDock Vina. AutoDock 4 consists of autodock to perform docking of ligand to set of grids describing target protein, and autogrid to pre calculate these grids.

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