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Preclinical study of human umbilical cord mesenchymal stem cell sheets for the recovery of ischemic heart tissue.

Shuang Gao | Yongqiang Jin | Jianlin Ma | Juan Wang | Jing Wang | Zehua Shao | Taibing Fan | Mingkui Zhang | Dehua Chang
Stem cell research & therapy | 2022

Human umbilical cord mesenchymal stem cells (hUC-MSCs) have been widely used due to their multipotency, a broad range of sources, painless collection, and compliance with standard amplification. Cell sheet technology is a tissue engineering methodology requiring scaffolds free, and it provides an effective method for cell transplantation. To improve the therapeutic efficacy, we combined hUC-MSCs with cell sheet technology to evaluate the safety and efficacy of hUC-MSC sheets in preclinical studies using appropriate animal models.

Pubmed ID: 35690871

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SH-SY5Y (tool)

RRID:CVCL_0019

Cell line SH-SY5Y is a Cancer cell line with a species of origin Homo sapiens (Human)

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NU/J (tool)

RRID:IMSR_JAX:002019

Mus musculus with name NU/J from IMSR.

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HUVEC-C (tool)

RRID:CVCL_2959

Cell line HUVEC-C is a Finite cell line with a species of origin Homo sapiens

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