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Naringin Regulates Microglia BV-2 Activation and Inflammation via the JAK/STAT3 Pathway.

Li Li | Ru Liu | Jing He | Jing Li | Juan Guo | Yun Chen | Ke Ji
Evidence-based complementary and alternative medicine : eCAM | 2022

Microglial BV-2 cells are activated in the brain following insomnia. Naringin (NAR) is a polymethoxylated flavonoid that is also commonly found in citrus fruits and is known for its antioxidant potential. However, the effect of NAR on microglial cells has rarely been studied in the brain of an organism after insomnia. This study aimed to investigate the effects and potential mechanisms of action of NAR on microglial cell activation and inflammation.

Pubmed ID: 35646153

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BV-2 (tool)

RRID:CVCL_0182

Cell line BV-2 is a Transformed cell line with a species of origin Mus musculus (Mouse)

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