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Arabidopsis cryptochrome 2 forms photobodies with TCP22 under blue light and regulates the circadian clock.

Weiliang Mo | Junchuan Zhang | Li Zhang | Zhenming Yang | Liang Yang | Nan Yao | Yong Xiao | Tianhong Li | Yaxing Li | Guangmei Zhang | Mingdi Bian | Xinglin Du | Zecheng Zuo
Nature communications | 2022

Cryptochromes are blue light receptors that regulate plant growth and development. They also act as the core components of the central clock oscillator in animals. Although plant cryptochromes have been reported to regulate the circadian clock in blue light, how they do so is unclear. Here we show that Arabidopsis cryptochrome 2 (CRY2) forms photobodies with the TCP22 transcription factor in response to blue light in plant cells. We provide evidence that PPK kinases influence the characteristics of these photobodies and that together these components, along with LWD transcriptional regulators, can positively regulate the expression of CCA1 encoding a central component of the circadian oscillator.

Pubmed ID: 35551190

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BioDare2 (tool)

RRID:SCR_027193

Data analysis resource and repository for biological data related to circadian rhythms, sharing public data from over 10,000 experiments (in 2025). The main features of BioDare2 are: fast analysis of rhythmic data (rhythm detection and period, phase, amplitude), timeseries processing, attractive visualizations, simple data description, data sharing with permalinks, easy data uploads and a modern UI.

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RRID:CVCL_0063

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Cry1tm1Jhjh/Cry1+; Cry2tm1Jhjh/Cry2tm1Jhjh (tool)

RRID:MGI:4943717

Allele Detail: Targeted This is a legacy resource.

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