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Co-deficiency of B7-H3 and B7-H4 identifies high CD8 + T cell infiltration and better prognosis in pancreatic cancer.

Shuping Si | Lei Wang | Hui Cao | Yuhua Xu | Qiang Zhan
BMC cancer | 2022

Immunotherapy is a novel hotspot for the treatment of pancreatic adenocarcinoma (PAAD). However, potential biomarkers which could identify the inflamed tumor microenvironment (TME) are urgently required.

Pubmed ID: 35219310

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Associated grants

  • Agency: Foundation for Innovative Research Groups of the National Natural Science Foundation of China,
    Id: 81773227

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This is a list of tools and resources that we have found mentioned in this publication.


Gene Expression Profiling Interactive Analysis (tool)

RRID:SCR_018294

Web server for cancer and normal gene expression profiling and interactive analyses. Interactive web server for analyzing RNA sequencing expression data of tumors and normal samples from TCGA and GTEx projects, using standard processing pipeline. Provides customizable functions such as tumor or normal differential expression analysis, profiling according to cancer types or pathological stages, patient survival analysis, similar gene detection, correlation analysis and dimensionality reduction analysis.

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xCell (tool)

RRID:SCR_026446

Software R package for generating cell type scores and R scripts for development of xCell. Web tool that performs cell type enrichment analysis from gene expression data for immune and stroma cell types. Used for Cell types enrichment analysis.

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