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Publication

Pamiparib Monotherapy for Patients with Germline BRCA1/2-Mutated Ovarian Cancer Previously Treated with at Least Two Lines of Chemotherapy: A Multicenter, Open-Label, Phase II Study.

Xiaohua Wu | Jianqing Zhu | Jing Wang | Zhongqiu Lin | Rutie Yin | Wei Sun | Qi Zhou | Songling Zhang | Danbo Wang | Hong Shi | Yunong Gao | Yi Huang | Guiling Li | Xiuli Wang | Ying Cheng | Ge Lou | Qinglei Gao | Li Wang | Xiuping Du | Mei Pan | Xiyan Mu | Li Li | Miao Li | Song Mu | Beihua Kong
Clinical cancer research : an official journal of the American Association for Cancer Research | 2022

Phase I results of this phase I/II study showed that pamiparib 60 mg twice a day had antitumor activity and an acceptable safety profile in Chinese patients with advanced cancer, including epithelial ovarian cancer.

Pubmed ID: 34844979

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WinNonlin (tool)

RRID:SCR_024504

Software to automate repetitive analysis steps and is widely considered the industry standard for NCA, TK, and PK/PD modeling. Used as non-compartmental analysis (NCA), pharmacokinetic/pharmacodynamic (PK/PD), and toxicokinetic (TK) modeling tool.

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The Stimulating Peripheral Activity to Relieve Conditions (SPARC) effort is the result of National Institutes of Health’s (NIH) drive to map out the neural circuitry responsible for visceral control in higher vertebrates. The SPARC Anatomy Working Group (SAWG) is responsible for the integrity of anatomical knowledge in SPARC

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