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New Steroidal Saponins Isolated from the Rhizomes of Paris mairei.

Yang Liu | Pengcheng Qiu | Minchang Wang | Yunyang Lu | Hao He | Haifeng Tang | Bang-Le Zhang
Molecules (Basel, Switzerland) | 2021

The genus Paris is an excellent source of steroidal saponins that exhibit various bioactivities. Paris mairei is a unique species and has been widely used as folk medicine in Southwest China for a long time. With the help of chemical methods and modern spectra analysis, five new steroidal saponins, pamaiosides A-E (1-5), along with five known steroidal saponins 6-10, were isolated from the rhizomes of Paris mairei. The cytotoxicity of all the new saponins was evaluated against human pancreatic adenocarcinoma PANC-1 and BxPC3 cell lines.

Pubmed ID: 34770773

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Associated grants

  • Agency: National Natural Science Foundation of China,
    Id: 81973192
  • Agency: National Natural Science Foundation of China,
    Id: 81903862
  • Agency: Shaanxi Province Key Research and Development Projects of China,
    Id: No.2021ZDLSF04-07
  • Agency: Shaanxi Province Key Research and Development Projects of China,
    Id: No. 2020SF-311

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This is a list of tools and resources that we have found mentioned in this publication.


BxPC-3 (tool)

RRID:CVCL_0186

Cell line BxPC-3 is a Cancer cell line with a species of origin Homo sapiens (Human)

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