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The clinical application of PIVKA-II in hepatocellular carcinoma and chronic liver diseases: A multi-center study in China.

Jun Ji | Lijuan Liu | Feifei Jiang | Xue Wen | Yu Zhang | Shengcong Li | Jinli Lou | Ying Wang | Ning Liu | Qiuyan Guo | Yongmei Jia | Chunfang Gao
Journal of clinical laboratory analysis | 2021

Due to the absence of specific symptoms and low survival rate, efficient biomarkers for hepatocellular carcinoma (HCC) diagnosis are urgently required. The purpose of this study was to evaluate the diagnostic performance of protein induced by vitamin K absence or antagonist-II (PIVKA-II) and to determine the optimal cutoff values for HBV infection-related HCC.

Pubmed ID: 34590755

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Abbott Diagnostics (tool)

RRID:SCR_008392

Company offering a broad range of instrument systems and diagnostic tests for hospitals, reference labs, blood banks, physician offices and clinics to aid in the diagnosis of a range of serious health issues such as infectious diseases, cancer, and diabetes, as well as monitor other important indicators of health.

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MedCalc (tool)

RRID:SCR_015044

Statistical software for ROC curve analysis. MedCalc performs several statistical tests such as method comparison, method evaluation, reference intervals, and meta-analysis.

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