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The cholesterol esterification inhibitor avasimibe suppresses tumour proliferation and metastasis via the E2F-1 signalling pathway in prostate cancer.

Kangping Xiong | Gang Wang | Tianchen Peng | Fenfang Zhou | Siming Chen | Wei Liu | Lingao Ju | Yu Xiao | Kaiyu Qian | Xinghuan Wang
Cancer cell international | 2021

New effective drugs for prostate cancer (PCa) treatment are urgently needed. Avasimibe was recently identified as a promising drug for anticancer therapies. The main purpose of this study was to explore the effects and the underlying mechanisms of avasimibe in prostate cancer.

Pubmed ID: 34461908

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