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IQGAP2 acts as an independent prognostic factor and is related to immunosuppression in DLBCL.

Tianjiao Tang | Jing Wang | Lidan Zhang | Ying Cheng | Laura Saleh | Yanni Gu | Hongbin Zhang
BMC cancer | 2021

Almost one-third of patients with diffuse large B-cell lymphoma (DLBCL) cannot be cured with initial therapy and will eventually succumb to the disease. Further elaboration of prognostic markers of DLBCL will provide therapeutic targets. IQ motif-containing GTPase activating protein 2 (IQGAP2) acts as a tumour suppressor in hepatocellular, prostate, and gastric cancers. However, the role of IQGAP2 in DLBCL remains unclear.

Pubmed ID: 34034707

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