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Berberine Slows the Progression of Prediabetes to Diabetes in Zucker Diabetic Fatty Rats by Enhancing Intestinal Secretion of Glucagon-Like Peptide-2 and Improving the Gut Microbiota.

Ying Wang | Haiyi Liu | Miaoyan Zheng | Yanhui Yang | Huizhu Ren | Yan Kong | Shanshan Wang | Jingyu Wang | Yingying Jiang | Juhong Yang | Chunyan Shan
Frontiers in endocrinology | 2021

Berberine is a plant alkaloid that has multiple beneficial effects against intestine inflammation. In our previous study, we have found that berberine also possesses an antidiabetic effect. However, whether berberine is useful in the prevention of type 2 diabetes mellitus (T2DM) through its effect on intestine endocrine function and gut microbiota is unclear.

Pubmed ID: 34025574

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