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Casein Kinase 2-Interacting Protein-1 Alleviates High Glucose-Reduced Autophagy, Oxidative Stress, and Apoptosis in Retinal Pigment Epithelial Cells via Activating the p62/KEAP1/NRF2 Signaling Pathway.

Xia Zhao | Jing Wang | Pei Li | Liying Tang | Yuzhi Bai
Journal of ophthalmology | 2021

Casein kinase 2-interacting protein-1 (CKIP-1) has been proved to be associated with complications of diabetes. Diabetic retinopathy is a main diabetic complication which usually leads to blindness. The current study aims to investigate the role of CKIP-1 in high glucose-treated retinal pigment epithelial (RPE) cells which is a component of blood-retinal barriers.

Pubmed ID: 33628480

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BioVision (tool)

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ARPE-19 (tool)

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Cell line ARPE-19 is a Spontaneously immortalized cell line with a species of origin Homo sapiens (Human)

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