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A CRISPR-Cas12a-based specific enhancer for more sensitive detection of SARS-CoV-2 infection.

Weiren Huang | Lei Yu | Donghua Wen | Dong Wei | Yangyang Sun | Huailong Zhao | Yu Ye | Wei Chen | Yongqiang Zhu | Lijun Wang | Li Wang | Wenjuan Wu | Qianqian Zhao | Yong Xu | Dayong Gu | Guohui Nie | Dongyi Zhu | Zhongliang Guo | Xiaoling Ma | Liman Niu | Yikun Huang | Yuchen Liu | Bo Peng | Renli Zhang | Xiuming Zhang | Dechang Li | Yang Liu | Guoliang Yang | Lanzheng Liu | Yunying Zhou | Yunshan Wang | Tieying Hou | Qiuping Gao | Wujiao Li | Shuo Chen | Xuejiao Hu | Mei Han | Huajun Zheng | Jianping Weng | Zhiming Cai | Xinxin Zhang | Fei Song | Guoping Zhao | Jin Wang
EBioMedicine | 2020

Real-time reverse transcription-PCR (rRT-PCR) has been the most effective and widely implemented diagnostic technology since the beginning of the COVID-19 pandemic. However, fuzzy rRT-PCR readouts with high Ct values are frequently encountered, resulting in uncertainty in diagnosis.

Pubmed ID: 33045467

Research resources used in this publication

None found

Additional research tools detected in this publication

Antibodies used in this publication

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None

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This is a list of tools and resources that we have found mentioned in this publication.


ggplot2 (tool)

RRID:SCR_014601

Open source software package for statistical programming language R to create plots based on grammar of graphics. Used for data visualization to break up graphs into semantic components such as scales and layers.

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