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Nestin represents a potential marker of pulmonary vascular remodeling in pulmonary arterial hypertension associated with congenital heart disease.

Jing-Jing Zhou | Huang Li | Yu-Ling Qian | Rui-Lin Quan | Xiao-Xi Chen | Li Li | Yue Li | Pei-He Wang | Xian-Min Meng | Xiao-Li Jing | Jian-Guo He
Journal of molecular and cellular cardiology | 2020

Reportedly, nestin was re-expressed in proliferative synthetic-type pulmonary artery smooth muscle cells (PASMCs) and obligatory for PASMC proliferation in pulmonary arterial hypertension (PAH). Accordingly, nestin is increased in pulmonary vascular lesions of congenital heart disease (CHD)-associated PAH patients. We tested the hypothesis whether nestin was re-expressed in proliferative synthetic-type PASMCs and associated with pulmonary vascular remodeling in CHD-PAH.

Pubmed ID: 32950539

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ProteinPilot Software (tool)

RRID:SCR_018681

Software tool for protein identification and relative protein expression analysis. Used in protein research to identify proteins and search large numbers of post translational modifications. Compatible with all proteomics MS/MS systems.

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SD (tool)

RRID:RGD_70508

Rattus norvegicus with name SD from RGD.

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