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Fosaprepitant versus aprepitant in the prevention of chemotherapy-induced nausea and vomiting in patients receiving cisplatin-based chemotherapy: a multicenter, randomized, double-blind, double-simulated, positive-controlled phase III trial.

Zhonghan Zhang | Yunpeng Yang | Ping Lu | Xiaoqin Li | Jianhua Chang | Rongsheng Zheng | Lei Zhou | Shaoshui Chen | Xiaopin Chen | Biyong Ren | Wei Gu | Xiaodong Jiang | Jiyong Peng | Miaolong Huang | Guosheng Feng | Peng Shen | Qingyuan Zhang | Baihong Zhang | Yan Huang | Jingdong He | Yinglan Chen | Jingxu Cao | Hong Wang | Wei Li | Huiping Wan | Kejun Nan | Zijun Liao | Cuiying Zhang | Zhong Lin | Diansheng Zhong | Qing Xu | Hailong Liu | Tao Sun | Yanming Deng | Li Zhang
Annals of translational medicine | 2020

To establish the role of antiemetic therapy with neurokinin-1 (NK-1) receptor antagonists (RAs) in Chinese patients associated with cisplatin-base chemotherapy regimens, this study evaluated the efficacy and safety of single-dose intravenous fosaprepitant-based triple antiemetic regimen to a 3-day orally aprepitant-based antiemetic triplet schedule for the prevention of chemotherapy-induced nausea and vomiting (CINV).

Pubmed ID: 32309381

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RRID:SCR_008567

Software platform to explore, analyze and visualize data. SAS 9.4 is part of SAS Platform. Standardized data governance and management from statistical software company SAS.

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