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Comparison of paired cerebrospinal fluid and serum cell-free mitochondrial and nuclear DNA with copy number and fragment length.

Aolong Chen | Jun Li | Lei Wang | Qin Huang | Jiajin Zhu | Shumeng Wen | Jianxin Lyu | Wenhe Wu
Journal of clinical laboratory analysis | 2020

Most studies on cell-free DNA (cfDNA) were only for single body fluids; however, the differences in cfDNA distribution between two body fluids are rarely reported. Hence, in this work, we compared the differences in cfDNA distribution between cerebrospinal fluid (CSF) and serum of patients with brain-related diseases.

Pubmed ID: 32052892

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Associated grants

  • Agency: Zhejiang Xinmiao Talent Projects,
    Id: 2017R413073
  • Agency: Wenzhou Science and Technology Planning Project,
    Id: Y20170249
  • Agency: National Natural Science Foundation of China,
    Id: 81101148
  • Agency: National Natural Science Foundation of China,
    Id: 81670712

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Bio-Rad QuantaSoft Analysis Pro (tool)

RRID:SCR_025321

Software analysis tool that enables data analysis of multiplex experiments and advanced applications and assay strategies for Droplet Digital PCR (ddPCR). For use with data files generated on QX100 or QX200 Droplet Reader using QuantSoft Standard Edition Software versions 1.4 or later.

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