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Increased mortality in elderly patients with acute respiratory distress syndrome is not explained by host response.

Laura R A Schouten | Lieuwe D J Bos | A Serpa Neto | Lonneke A van Vught | Maryse A Wiewel | Arie J Hoogendijk | Marc J M Bonten | Olaf L Cremer | Janneke Horn | Tom van der Poll | Marcus J Schultz | Roelie M Wösten-van Asperen | MARS consortium
Intensive care medicine experimental | 2019

Advanced age is associated with increased mortality in acute respiratory distress syndrome (ARDS) patients. Preclinical studies suggest that the host response to an injurious challenge is age-dependent. In ARDS patients, we investigated whether the association between age and mortality is mediated through age-related differences in the host response.

Pubmed ID: 31664603

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RRID:SCR_002309

Registry and results database of federally and privately supported clinical trials conducted in United States and around world. Provides information about purpose of trial, who may participate, locations, and phone numbers for more details. This information should be used in conjunction with advice from health care professionals.Offers information for locating federally and privately supported clinical trials for wide range of diseases and conditions. Research study in human volunteers to answer specific health questions. Interventional trials determine whether experimental treatments or new ways of using known therapies are safe and effective under controlled environments. Observational trials address health issues in large groups of people or populations in natural settings. ClinicalTrials.gov contains trials sponsored by National Institutes of Health, other federal agencies, and private industry. Studies listed in database are conducted in all 50 States and in 178 countries.

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