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CortiWatch: watch-based cortisol tracker.

Paul Rice | Sayali Upasham | Badrinath Jagannath | Roshan Manuel | Madhavi Pali | Shalini Prasad
Future science OA | 2019

Sweat-based analytics have recently caught the attention of researchers and medical professionals alike because they do not require professionally trained personnel or invasive collection techniques to obtain a sample. The following presents a small form-factor biosensor for reporting physiological ranges of cortisol present in ambient sweat (8-151 ng/ml). This device obtains cortisol measurements through low volumes of unstimulated sweat from the user's wrist. We designed a potentiostatic circuit on a printed circuit board to perform electrochemical testing techniques. The detection modality developed for quantifying sensor response to varying cortisol concentrations is a current based electrochemical technique, chronoamperometry (CA). From the results, the sensor can detect cortisol in the physiologically relevant ranges of cortisol; thus, the sensor is a noninvasive, label free, cost-effective solution for tracking cortisol levels for circadian diagnostics.

Pubmed ID: 31608155

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GraphPad Prism (tool)

RRID:SCR_002798

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Abcam (tool)

RRID:SCR_012931

A commercial antibody supplier which supplies primary and secondary antibodies, biochemicals, proteins, peptides, lysates, immunoassays and other kits.

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