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Delivery luteolin with folacin-modified nanoparticle for glioma therapy.

Cong Wu | Qian Xu | Xinyue Chen | Jiagang Liu
International journal of nanomedicine | 2019

Glioblastoma mutliforme is the most common and has the poorest prognosis of any malignant tumor of the central nervous system. Luteolin, the most abundant xanthone extracted from vegetables and medicinal plants, has been shown to have treatment effects in various cancer cell types. Luteolin is however, hydrophobic and has poor biocompatibility, which leads to low bioavailability.

Pubmed ID: 31571861

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ChemAxon (tool)

RRID:SCR_004111

Commercial organization that provides cheminformatics software platforms, applications and services to optimize the value of chemistry information in life science and other R&D. This software enables structure visualization and management, property predictions and calculations, virtual synthesis, screening, clustering and drug design.

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GL261 (tool)

RRID:CVCL_Y003

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SD (tool)

RRID:RGD_70508

Rattus norvegicus with name SD from RGD.

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