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N-Palmitoylethanolamide-Oxazoline Protects against Middle Cerebral Artery Occlusion Injury in Diabetic Rats by Regulating the SIRT1 Pathway.

Roberta Fusco | Maria Scuto | Marika Cordaro | Ramona D'Amico | Enrico Gugliandolo | Rosalba Siracusa | Alessio Filippo Peritore | Rosalia Crupi | Daniela Impellizzeri | Salvatore Cuzzocrea | Rosanna Di Paola
International journal of molecular sciences | 2019

Diabetes causes various macrovascular and microvascular alterations, often culminating in major clinical complications (first of all, stroke) that lack an effective therapeutic intervention. N-palmitoylethanolamide-oxazoline (PEA-OXA) possesses anti-inflammatory and potent neuroprotective effects. Although recent studies have explained the neuroprotective properties of PEA-OXA, nothing is known about its effects in treating cerebral ischemia.

Pubmed ID: 31569558

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Promega (tool)

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Molecular Probes (tool)

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An Antibody supplier and subset of ThermoFisher Scientific which provides fluorescence reagents for various experiments and methods.

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WI (tool)

RRID:RGD_13508588

Rattus norvegicus with name WI from RGD.

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