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Publication

A novel heat shock protein 90 inhibitor potently targets adrenocortical carcinoma tumor suppression.

Ton Wang | Chitra Subramanian | Brian S J Blagg | Mark S Cohen
Surgery | 2020

Adrenocortical carcinoma is an aggressive cancer with a poor prognosis. Long noncoding RNAs are differentially expressed in cancer patients and contribute to cellular homeostasis, survival, and metastasis. We hypothesize that our novel C-terminal Hsp90 inhibitor KU758 can effectively target adrenocortical carcinoma cells and favorably alter long noncoding RNA expression.

Pubmed ID: 31561992

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Associated grants

  • Agency: NCI NIH HHS, United States
    Id: R01 CA120458
  • Agency: NCI NIH HHS, United States
    Id: R01 CA213566
  • Agency: NCI NIH HHS, United States
    Id: R01 CA216919
  • Agency: NCI NIH HHS, United States
    Id: T32 CA009672

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NCI-H295R (tool)

RRID:CVCL_0458

Cell line NCI-H295R is a Cancer cell line with a species of origin Homo sapiens (Human)

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SW13 (tool)

RRID:CVCL_0542

Cell line SW13 is a Cancer cell line with a species of origin Homo sapiens (Human)

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MRC-5 (tool)

RRID:CVCL_0440

Cell line MRC-5 is a Finite cell line with a species of origin Homo sapiens

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