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Publication

Total glucosides of peony improve ovalbumin-induced allergic asthma by inhibiting mast cell degranulation.

Qiyang Shou | Jiali Lang | Lu Jin | Mingsun Fang | Beibei Cao | Yueqin Cai | Zhunan Ni | Fengmei Qiu | Changyu Li | Gang Cao | Huiying Fu
Journal of ethnopharmacology | 2019

Paeonia lactiflora Pall. (peony) is a medicinal plant used in the Xiaoqinglong decoction, a commonly prescribed traditional Chinese medicine for asthma. The main active ingredients of peony roots-described as the total glucosides of peony (TGP)-have anti-inflammatory, immunomodulatory, and protective effects on endothelial cells, and they are known to improve rheumatoid arthritis. This study explored the underlying mechanism of TGP activity in the treatment of allergic asthma.

Pubmed ID: 31377261

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