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RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer.

Qingyuan Li | Qiuhua Lai | Chengcheng He | Yuxin Fang | Qun Yan | Yue Zhang | Xinke Wang | Chuncai Gu | Yiqing Wang | Liangying Ye | Lu Han | Xin Lin | Junsheng Chen | Jianqun Cai | Aimin Li | Side Liu
Journal of experimental & clinical cancer research : CR | 2019

Runt-related transcription factor 1 (RUNX1) plays the roles of an oncogene and an anti-oncogene in epithelial tumours, and abnormally elevated RUNX1 has been suggested to contribute to the carcinogenesis of colorectal cancer (CRC). However, the mechanism remains unclear.

Pubmed ID: 31370857

Research resources used in this publication

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