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Publication

The retinal environment induces microglia-like properties in recruited myeloid cells.

Scott W McPherson | Neal D Heuss | Ute Lehmann | Heidi Roehrich | Md Abedin | Dale S Gregerson
Journal of neuroinflammation | 2019

Microglia are essential to the development of the CNS and its homeostasis. Our prior findings suggested a niche model to describe the behaviors of retinal microglia. Here, we ask whether new myeloid cells recruited to the retina are constrained to resemble endogenous microglia morphologically and functionally.

Pubmed ID: 31325968

Research resources used in this publication

None found

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Associated grants

  • Agency: NEI NIH HHS, United States
    Id: R01 EY025209
  • Agency: NEI NIH HHS, United States
    Id: P30 EY011374
  • Agency: NEI NIH HHS, United States
    Id: P30-EY011374
  • Agency: NEI NIH HHS, United States
    Id: R01-EY021003
  • Agency: NEI NIH HHS, United States
    Id: R01 EY021003
  • Agency: NEI NIH HHS, United States
    Id: R01-EY025209
  • Agency: NEI NIH HHS, United States
    Id: T32-EY07133-17
  • Agency: NEI NIH HHS, United States
    Id: T32 EY007133

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BD Biosciences (tool)

RRID:SCR_013311

An Antibody supplier

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B6.129P2(Cg)-Cx3cr1tm2.1(cre/ERT2)Litt/WganJ (tool)

RRID:IMSR_JAX:021160

Mus musculus with name B6.129P2(Cg)-Cx3cr1tm2.1(cre/ERT2)Litt/WganJ from IMSR.

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The Stimulating Peripheral Activity to Relieve Conditions (SPARC) effort is the result of National Institutes of Health’s (NIH) drive to map out the neural circuitry responsible for visceral control in higher vertebrates. The SPARC Anatomy Working Group (SAWG) is responsible for the integrity of anatomical knowledge in SPARC

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