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Pharmacokinetics of cucurbitacin B from Trichosanthes cucumerina L. in rats.

Natthaphon Hunsakunachai | Nitra Nuengchamnong | Weena Jiratchariyakul | Tanawan Kummalue | Phisit Khemawoot
BMC complementary and alternative medicine | 2019

Cucurbitacin B is the major bioactive constituent in Trichosanthes cucumerina L. fruits, which the pharmacological properties have been studied for decades particularly an anti-tumor activity. The pharmacokinetic profile of this compound is still limited and investigation is needed for further phytopharmaceutical product development. This study aimed to investigate the pharmacokinetic profile of cucurbitacin B after administering the compound at different doses and routes to rats.

Pubmed ID: 31272429

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G*Power (tool)

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Data analytics software to compute statistical power analyses for many commonly used statistical tests in social and behavioral research. It can also be used to compute effect sizes and to graphically display the results of power analyses.

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WI (tool)

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Rattus norvegicus with name WI from RGD.

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