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Diarrhoea: interventions, consequences and epidemiology in the intensive care unit (DICE-ICU): a protocol for a prospective multicentre cohort study.

Joanna C Dionne | Kristen Sullivan | Lawrence Mbuagbaw | Alyson Takaoka | Erick Huaileigh Duan | Waleed Alhazzani | John W Devlin | Matthew Duprey | Paul Moayyedi | David Armstrong | Lehana Thabane | Jennifer L Y Tsang | Roman Jaeschke | Cindy Hamielec | Tim Karachi | Rodrigo Cartin-Ceba | John Muscedere | Mohammed Saeed Saad Alshahrani | Deborah J Cook
BMJ open | 2019

Diarrhoea is a frequent concern in the intensive care unit (ICU) and is associated with prolonged mechanical ventilation, increased length of ICU stay, skin breakdown and renal dysfunction. However, its prevalence, aetiology and prognosis in the critically ill have been poorly studied. The primary objectives of this study are to determine the incidence, risk factors and consequences of diarrhoea in critically ill adults. The secondary objectives are to estimate the incidence of Clostridium difficile-associated diarrhoea (CDAD) in ICU patients and to validate the Bristol Stool Chart and Bliss Stool Classification System characterising bowel movements in the ICU. Our primary outcome is the incidence of diarrhoea . Our secondary outcomes include: CDAD, ICU and hospital mortality and ICU and hospital length of stay.

Pubmed ID: 31248929

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Associated grants

  • Agency: CIHR, Canada

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SPSS (tool)

RRID:SCR_002865

Software package used for interactive, or batched, statistical analysis in social science, health sciences and marketing. Software platform offers advanced statistical analysis, a library of machine-learning algorithms, text analysis, open-source extensibility, integration with big data and deployment into applications.Versions that were produced by SPSS Inc. before the IBM acquisition (Versions 18 and earlier) would be given origin or publisher of SPSS Inc. in Chicago.

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