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Efficacy and safety with ticagrelor in patients with prior myocardial infarction in the approved European label: insights from PEGASUS-TIMI 54.

Mikael Dellborg | Marc P Bonaca | Robert F Storey | P Gabriel Steg | Kyung A Im | Marc Cohen | Deepak L Bhatt | Ton Oude Ophuis | Andrezej Budaj | Christian Hamm | Jindrich Spinar | Robert G Kiss | José Lopez-Sendon | Gabriel Kamensky | Frans Van de Werf | Diego Ardissino | Frederic Kontny | Gilles Montalescot | Per Johanson | Olof Bengtsson | Anders Himmelmann | Eugene Braunwald | Marc S Sabatine
European heart journal. Cardiovascular pharmacotherapy | 2019

In PEGASUS-TIMI 54, ticagrelor significantly reduced the risk of the composite of major adverse cardiovascular (CV) events by 15-16% in stable patients with a prior myocardial infarction (MI) 1-3 years earlier. We report the efficacy and safety in the subpopulation recommended for treatment in the European (EU) label, i.e. treatment with 60 mg b.i.d. initiated up to 2 years from the MI, or within 1 year after stopping previous adenosine diphosphate receptor inhibitor treatment.

Pubmed ID: 31218354

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RRID:SCR_002309

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