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Safety and efficacy of ex vivo expanded CD34+ stem cells in murine and primate models.

Yu Zhang | Bin Shen | Xin Guan | Meng Qin | Zhihua Ren | Yupo Ma | Wei Dai | Xinxin Ding | Yongping Jiang
Stem cell research & therapy | 2019

Hematopoietic stem cell (HSC) transplantation has been widely applied to the treatment of malignant blood diseases. However, limited number of functional HSCs hinders successful transplantation. The purpose of our current study is to develop a new and cost-efficient medium formulation that could greatly enhance the expansion of HSCs while retaining their long-term repopulation and hematopoietic properties for effective clinical transplantation.

Pubmed ID: 31196160

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FlowJo (tool)

RRID:SCR_008520

Software for single-cell flow cytometry analysis. Its functions include management, display, manipulation, analysis and publication of the data stream produced by flow and mass cytometers.

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