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Extracellular matrix from decellularized mesenchymal stem cells improves cardiac gene expressions and oxidative resistance in cardiac C-kit cells.

Wai Hoe Ng | Rajesh Ramasamy | Yoke Keong Yong | Siti Hawa Ngalim | Vuanghao Lim | Bakiah Shaharuddin | Jun Jie Tan
Regenerative therapy | 2019

Myocardial infarction remains the number one killer disease worldwide. Cellular therapy using cardiac c-kit cells (CCs) are capable of regenerating injured heart. Previous studies showed mesenchymal stem cell-derived (MSC) extracellular matrices can provide structural support and are capable of regulating stem cell functions and differentiation. This study aimed to evaluate the effects of human MSC-derived matrices for CC growth and differentiation.

Pubmed ID: 31193142

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C57BL/6N (tool)

RRID:MGI:2159965

laboratory mouse with name C57BL/6N from MGI.

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