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High throughput sequencing identifies breast cancer-secreted exosomal LncRNAs initiating pulmonary pre-metastatic niche formation.

Tongbao Feng | Ping Zhang | Yingxin Sun | Yan Wang | Jichun Tong | Hong Dai | Zichun Hua
Gene | 2019

Increasing evidence indicated that cancer-secreted exosomes played an important role in tumor metastasis. However, the function of exosomes in breast cancer pulmonary metastasis remains unknown. The aim of the study was to investigate the role of exosome-derived from breast cancer-secreted long non-coding RNAs (LncRNAs) on pre-metastatic niche formation in pulmonary metastasis.

Pubmed ID: 31176731

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