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DNA methylation screening after roux-en Y gastric bypass reveals the epigenetic signature stems from genes related to the surgery per se.

C F Nicoletti | M A S Pinhel | A Diaz-Lagares | F F Casanueva | A Jácome | V C Pinhanelli | B A P de Oliveira | A B Crujeiras | C B Nonino
BMC medical genomics | 2019

Obesity has been associated with gene methylation regulation. Recent studies have shown that epigenetic signature plays a role in metabolic homeostasis after Roux-en Y gastric bypass (RYGB). To conduct a genome-wide epigenetic analysis in peripheral blood to investigate whether epigenetic changes following RYGB stem from weight loss or the surgical procedure per se.

Pubmed ID: 31133015

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