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Association between fat mass through adolescence and arterial stiffness: a population-based study from The Avon Longitudinal Study of Parents and Children.

Frida Dangardt | Marietta Charakida | Georgios Georgiopoulos | Scott T Chiesa | Alicja Rapala | Kaitlin H Wade | Alun D Hughes | Nicholas J Timpson | Konstantinos Pateras | Nick Finer | Naveed Sattar | George Davey Smith | Debbie A Lawlor | John E Deanfield
The Lancet. Child & adolescent health | 2019

The link between adiposity, metabolic abnormalities, and arterial disease progression in children and adolescents remains poorly defined. We aimed to assess whether persistent high adiposity levels are associated with increased arterial stiffness in adolescence and any mediation effects by common metabolic risk factors.

Pubmed ID: 31126896

Research resources used in this publication

None found

Additional research tools detected in this publication

Antibodies used in this publication

None found

Associated grants

  • Agency: Medical Research Council, United Kingdom
    Id: MC_PC_19009
  • Agency: British Heart Foundation, United Kingdom
    Id: RG/10/004/28240
  • Agency: Medical Research Council, United Kingdom
    Id: MC_UU_00011/6
  • Agency: Medical Research Council, United Kingdom
    Id: MC_PC_15018
  • Agency: Medical Research Council, United Kingdom
    Id: G9815508
  • Agency: British Heart Foundation, United Kingdom
    Id: CS/15/6/31468
  • Agency: Medical Research Council, United Kingdom
    Id: MC_UU_12013/3

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ALSPAC (tool)

RRID:SCR_007260

A long-term health research project which follows pregnant women and their offspring in a continuous health and developmental study. More than 14,000 mothers enrolled during pregnancy in 1991 and 1992, and the health and development of their children has been followed in great detail. The ALSPAC families have provided a vast amount of genetic and environmental information over the years which can be made available to researchers globally.

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