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Delivery vehicle of muscle-derived irisin based on silk/calcium silicate/sodium alginate composite scaffold for bone regeneration.

Xianzhen Xin | Jiannan Wu | Ao Zheng | Delong Jiao | Yang Liu | Lingyan Cao | Xinquan Jiang
International journal of nanomedicine | 2019

Irisin is a cytokine produced by skeletal muscle and usually plays a pivotal role in inducing fat browning and regulating energy expenditure. In recent years, it was found that irisin might be the molecular entity responsible for muscle-bone connectivity and is useful in osteogenesis induction.

Pubmed ID: 30863071

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