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Analytical characterization and reference interval of an enzyme-linked immunosorbent assay for active von Willebrand factor.

Lisa N van der Vorm | Li Li | Dana Huskens | Walid Chayouâ | Hilde Kelchtermans | Philip G de Groot | Mark Roest | Jasper A Remijn | Bas de Laat
PloS one | 2019

Interaction of von Willebrand factor (VWF) with platelets requires a conformational change that exposes an epitope within the VWF A1 domain, enabling platelet glycoprotein Ibα binding. Quantification of this ''active" conformation of VWF has been shown to provide pathophysiological insight into conditions characterized by excessive VWF-platelet interaction.

Pubmed ID: 30759116

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Dako (tool)

RRID:SCR_013530

An Antibody supplier; Dako was purchased by Agilent in 2012 and several years later the websites began to reflect the Dako products as part of the Agilent catalog.

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