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PD-1/PD-L1 blockade rescue exhausted CD8+ T cells in gastrointestinal stromal tumours via the PI3K/Akt/mTOR signalling pathway.

Rui Zhao | Yinghan Song | Yong Wang | Yuqian Huang | Zhigui Li | Yaping Cui | Mengshi Yi | Lin Xia | Wen Zhuang | Xiaoting Wu | Yong Zhou
Cell proliferation | 2019

Although targeted therapy has revolutionized the treatment of gastrointestinal stromal tumours (GIST), it is almost never curative in GIST, and resistance commonly develops. One potential strategy is to combine targeted therapy with immunotherapy.

Pubmed ID: 30714229

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Quantity One 1-D Analysis Software (tool)

RRID:SCR_014280

Software used for Bio-Rad imaging systems to acquire, quantitate, and analyze a variety of data. The software allows automatic configuration of imaging systems with appropriate filters, lasers, LEDs, and other illumination sources. It also contains tools for automated analysis of tests and assays such as 1-D electrophoretic gels, western blots, and colony counts.

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