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TMEM16A is implicated in the regulation of coronary flow and is altered in hypertension.

Henry R Askew Page | Thomas Dalsgaard | Samuel N Baldwin | Thomas A Jepps | Oleksandr Povstyan | Søren P Olesen | Iain A Greenwood
British journal of pharmacology | 2019

Coronary artery disease leads to ischaemic heart disease and ultimately myocardial infarction. Thus, it is important to determine the factors that regulate coronary blood flow. Ca2+ -activated chloride channels contribute to the regulation of arterial tone; however, their role in coronary arteries is unknown. The aim of this study was to investigate the expression and function of the main molecular correlate of Ca2+ -activated chloride channels, TMEM16A, in rat coronary arteries.

Pubmed ID: 30710335

Additional research tools detected in this publication

None found

Antibodies used in this publication

Associated grants

  • Agency: British Heart Foundation, United Kingdom
    Id: FS/18/41/33762
  • Agency: Medical Research Council, United Kingdom
    Id: MR/K019074/1
  • Agency: British Heart Foundation, United Kingdom
    Id: PG/14/57/30992

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This is a list of tools and resources that we have found mentioned in this publication.


TMEM16A antibody (antibody)

RRID:AB_883075

This polyclonal targets TMEM16A antibody

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GraphPad Prism (software resource)

RRID:SCR_002798

Statistical analysis software that combines scientific graphing, comprehensive curve fitting (nonlinear regression), understandable statistics, and data organization. Designed for biological research applications in pharmacology, physiology, and other biological fields for data analysis, hypothesis testing, and modeling.

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SHR/NHsd (organism)

RRID:RGD_724574

Rattus norvegicus with name SHR/NHsd from RGD.

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Crl:WI (organism)

RRID:RGD_737929

Rattus norvegicus with name Crl:WI from RGD.

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