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Association of Hemoglobin A1c Levels With Use of Sulfonylureas, Dipeptidyl Peptidase 4 Inhibitors, and Thiazolidinediones in Patients With Type 2 Diabetes Treated With Metformin: Analysis From the Observational Health Data Sciences and Informatics Initiative.

Rohit Vashisht | Kenneth Jung | Alejandro Schuler | Juan M Banda | Rae Woong Park | Sanghyung Jin | Li Li | Joel T Dudley | Kipp W Johnson | Mark M Shervey | Hua Xu | Yonghui Wu | Karthik Natrajan | George Hripcsak | Peng Jin | Mui Van Zandt | Anthony Reckard | Christian G Reich | James Weaver | Martijn J Schuemie | Patrick B Ryan | Alison Callahan | Nigam H Shah
JAMA network open | 2018

Consensus around an efficient second-line treatment option for type 2 diabetes (T2D) remains ambiguous. The availability of electronic medical records and insurance claims data, which capture routine medical practice, accessed via the Observational Health Data Sciences and Informatics network presents an opportunity to generate evidence for the effectiveness of second-line treatments.

Pubmed ID: 30646124

Research resources used in this publication

None found

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Antibodies used in this publication

None found

Associated grants

  • Agency: NIGMS NIH HHS, United States
    Id: R01 GM101430
  • Agency: NCI NIH HHS, United States
    Id: R25 CA180993
  • Agency: NLM NIH HHS, United States
    Id: R01 LM006910
  • Agency: NLM NIH HHS, United States
    Id: R01 LM011369
  • Agency: NIDDK NIH HHS, United States
    Id: R01 DK098242

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RxNorm (tool)

RRID:SCR_006645

Ontology that provides a normalized naming system for generic and branded drugs and a tool for supporting semantic interoperation between drug terminologies and pharmacy knowledge base systems. It contains the names of prescription and many over-the-counter drugs available in the United States and links its names to many of the drug vocabularies commonly used in pharmacy management and drug interaction software. It can mediate messages between systems not using the same software and vocabulary. * RxNorm Download Files - contain data consistent with the 2013AB UMLS Metathesaurus Release Files. * RxNorm API - web service for accessing the current RxNorm data set. * RxNorm Browser (RxNav) - a browser for several drug information sources, including RxNorm, RxTerms and National Drug File - Reference Terminology (NDF-RT) . * Current Prescribable Content - subset of currently prescribable drugs found in RxNorm. * RxTerms Drug Interface Terminology - a drug interface terminology derived from RxNorm for prescription writing or medication history recording

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CohortMethod (tool)

RRID:SCR_018511

Software R package for performing new user cohort studies in observational database in OMOP Common Data Model.

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