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miR-1 inhibits the proliferation of breast cancer stem cells by targeting EVI-1.

Lei Wu | Tianyi Wang | Dongning He | Xiaoxi Li | Youhong Jiang
OncoTargets and therapy | 2018

Breast cancer stem cells (BCSCs) have been regarded as the key factor for treatment failure in breast cancer. The abnormal expression of miRNAs plays a significant role in different tumor types. However, the role of miR-1 in breast cancer remains poorly understood. The purpose of this study was to evaluate the effects of miR-1 on the proliferation and apoptosis of BCSCs.

Pubmed ID: 30584335

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This is a list of tools and resources that we have found mentioned in this publication.


TargetScan (tool)

RRID:SCR_010845

Web tool to predict biological targets of miRNAs by searching for presence of conserved 8mer, 7mer and 6mer sites that match seed region of each miRNA. Nonconserved sites are also predicted and sites with mismatches in seed region that are compensated by conserved 3' pairing. Used to search for predicted microRNA targets in mammals.

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Abcam (tool)

RRID:SCR_012931

A commercial antibody supplier which supplies primary and secondary antibodies, biochemicals, proteins, peptides, lysates, immunoassays and other kits.

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BD Biosciences (tool)

RRID:SCR_013311

An Antibody supplier

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MDA-MB-231 (tool)

RRID:CVCL_0062

Cell line MDA-MB-231 is a Cancer cell line with a species of origin Homo sapiens (Human)

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MDA-MB-231 (tool)

RRID:CVCL_0062

Cell line MDA-MB-231 is a Cancer cell line with a species of origin Homo sapiens (Human)

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NU/J (tool)

RRID:IMSR_JAX:002019

Mus musculus with name NU/J from IMSR.

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